I don’t read many comics these days, but I’ve really enjoyed the collections of Y: The Last Man. From Boing Boing, Cory Doctorow’s summary is as good as any:
The plot of Y: The Last Man is a pretty straightforward apocalyptic tale: one day, every man on earth drops dead, blood gushing from their noses and mouths, leaving no one behind but women, and one man, and one male monkey (his pet — a helper monkey he’s been training). The setup rapidly progresses into a gripping, funny, sad and lovely tale of the post-apocalyptic world.
It’s a particularly adult kind of comic, full of literary and pop references and witty dialogue. Via the aforementioned Boing Boing link, I learned that the first issue is available online (PDF). Even if you’ve never been a comic book reader, it’s worth taking five minutes to check out.